Do you have CONGENITAL
You're not alone.

Learn about a new, no cost research study

About the Study

Congenital adrenal hyperplasia (CAH) is a rare genetic disorder affecting the adrenal glands. People with CAH produce lower levels of cortisol, also known as “the stress hormone,” which has an effect on energy, blood pressure, and the body’s response to stress, illness and injury. While steroid medications can effectively replace the body’s cortisol, they can be difficult to balance and often produce unwanted side effects.

Right now, doctors at select centers in the U.S. are accepting participants for a new clinical research study. The study is for an investigational oral drug for CAH, designed to correct hormone imbalance and potentially reduce the necessary dose of traditional steroid medications. If you are 18 years of age or older, and have been diagnosed with classic CAH, you may qualify to participate. If you join, you will receive study-related care and medication at no cost, and will also be compensated for your time and travel.

Why Participate?

If you qualify and choose to join the study, you will receive study-related:

  • Evaluations of your Congenital Adrenal Hyperplasia (CAH) condition by a local specialist
  • Access to a new investigational oral drug for CAH only available through this study
  • All study-related care, medical exams and medication at no cost*
  • Compensation for your time and travel to attend study visits

* You do not need insurance to participate.

Frequent Questions
Clinical studies (also called clinical trials) are used to learn about the safety and effectiveness of possible new medications, medical devices, and medical procedures. Although there are many types of clinical trials, all must conform to strict rules set by the U.S. Food and Drug Administration (FDA). These rules help protect the rights and safety of those who volunteer to take part in clinical trials.
If you join the study, your participation will last about 10 weeks, and will require up to 5 scheduled visits to your local study center. Some of these visits will involve an overnight stay for which you will receive compensation and no-cost transportation to your local study center. Your study center will be able to discuss these visits with you in much more detail.
As with all clinical studies, your participation is completely voluntary and you may choose to leave the study at any time.
Yes, you will continue your current CAH treatment during the course of the study.
If you qualify and choose to participate, you will receive all study-related care (such as study medications and any visits to your study doctor’s office) at no cost to you. You will also be compensated for your time and travel to attend study visits.
The study is being sponsored by Spruce Biosciences (, a biopharmaceutical company based in San Francisco.
To see if you might qualify for the study, and to get connected with your local study center to discuss the study further, the next step is taking the pre-screening questionnaire. Please click here to get started.

See If You Qualify

To see if you might qualify for the study, and to get connected with the study center in your area to learn more, please take the questionnaire below.